Spondyloarthritis & psoriatic arthritis

Diagnostic delay and less intensive therapy for people with psoriatic arthritis compared with rheumatoid arthritis: a study nested within an English and Welsh audit data set

Ann Rheum DisPublished Matched cohort study

Authors' conclusion

Compared with patients with RA, patients with PsA have a longer duration of symptoms before referral and a longer interval between presentation to the GP and receiving a diagnosis.

Study context

Population
Patients in the National Early Inflammatory Arthritis Audit (England and Wales), May 2018 to October 31, 20191,250 polyarticular
Exposure
PsA vs rheumatoid arthritis (RA)
  • PsAn = 2,120
Outcome
Time to diagnosis
Methodological detailsmatched 1:1 on age and sex, nested within national audit data set
  • Matched 1:1 on age and sex
  • Nested within national audit data set

Main finding

Time from general practitioner (GP) presentation to diagnosis

Hazard ratio

0.87

95% CI 0.79–0.96

P = 0.007

By group

PsAvs RA
HR 0.87 (95% CI 0.79–0.96); P = 0.007

As reported in the abstract

Observational data: associations, not effects.

Further findings

OutcomeHR (95% CI)P value
Time to diagnosis once referrals received in secondary care0.86 (0.80–0.95)P = 0.002

DMARDs prescribed at baseline (polyarticular subgroup)

P < 0.001

OutcomeDifference (95% CI)
DAS28 (polyarticular subgroup) · 3 monthsRA higher at baseline0.27 (0.13–0.4)

Original publication

Diagnostic delay and less intensive therapy for people with psoriatic arthritis compared with rheumatoid arthritis: a study nested within an English and Welsh audit data set. Ann Rheum Dis. Published 29 March 2025. doi:10.1016/j.ard.2025.02.020

Composed by AI from the published abstract and checked against it. How Briefs are made →

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