Spondyloarthritis & psoriatic arthritis
Diagnostic delay and less intensive therapy for people with psoriatic arthritis compared with rheumatoid arthritis: a study nested within an English and Welsh audit data set
Authors' conclusion
Compared with patients with RA, patients with PsA have a longer duration of symptoms before referral and a longer interval between presentation to the GP and receiving a diagnosis.
Study context
- Population
- Patients in the National Early Inflammatory Arthritis Audit (England and Wales), May 2018 to October 31, 20191,250 polyarticular
- Exposure
- PsA vs rheumatoid arthritis (RA)
- PsAn = 2,120
- Outcome
- Time to diagnosis
Methodological detailsmatched 1:1 on age and sex, nested within national audit data set
- Matched 1:1 on age and sex
- Nested within national audit data set
Main finding
Time from general practitioner (GP) presentation to diagnosis
Hazard ratio
0.87
95% CI 0.79–0.96
P = 0.007
By group
PsAvs RA
HR 0.87 (95% CI 0.79–0.96); P = 0.007
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | P value | |
|---|---|---|---|
| Time to diagnosis once referrals received in secondary care | 0.86 (0.80–0.95) | P = 0.002 | |
| 0.512Hazard ratio (log scale) |
DMARDs prescribed at baseline (polyarticular subgroup)
P < 0.001
| Outcome | Difference (95% CI) | |
|---|---|---|
| DAS28 (polyarticular subgroup) · 3 monthsRA higher at baseline | 0.27 (0.13–0.4) | |
| −0.200.20.40.6Difference (linear scale) |
Original publication
Diagnostic delay and less intensive therapy for people with psoriatic arthritis compared with rheumatoid arthritis: a study nested within an English and Welsh audit data set. Ann Rheum Dis. Published 29 March 2025. doi:10. 1016/ j. ard. 2025. 02. 020
Composed by AI from the published abstract and checked against it. How Briefs are made →