Spondyloarthritis & psoriatic arthritis

Factors Associated With Diagnostic Delay in Axial Spondyloarthritis: Impact of Clinical Factors and Social Vulnerability

Arthritis Care Res (Hoboken)Published Retrospective cohort study

Authors' conclusion

Older age at back pain onset and peripheral arthritis were associated with shorter delay, whereas uveitis was associated with longer diagnostic delay. Patients with higher socioeconomic vulnerability had longer diagnostic delay independent of clinical factors.

Study context

Population
Patients meeting modified New York criteria for ankylosing spondylitis (AS) or 2009 ASAS criteria for axial spondyloarthritis (axSpA), Mass General Brigham health care system, December 1990–October 2021
Participants
554 patients
Outcome
Diagnostic delay (duration of back pain symptoms reported at diagnosis)
Methodological detailssingle health care system, ordinal logistic regression
  • Single health care system
  • Ordinal logistic regression

Main finding

As reported in the abstract

Factors associated with diagnostic delay (ordinal logistic regression)
Median diagnostic delay, years (IQR 1.1-10)
3.8
Peripheral arthritis, shorter delay: OR
0.65 (95% CI 0.45-0.93)
Older age at symptom onset, per five years, shorter delay: OR
0.83 (95% CI 0.78-0.88)
AS at diagnosis, longer delay: OR
1.85 (95% CI 1.30-2.63)
History of uveitis prior to diagnosis, longer delay: OR
2.77 (95% CI 1.73-4.52)
Higher social vulnerability (national Social Vulnerability Index (SVI) 80th to 99th percentiles), longer delay: OR
1.99 (95% CI 1.06-3.84)

Observational data: associations, not effects.

Original publication

Factors Associated With Diagnostic Delay in Axial Spondyloarthritis: Impact of Clinical Factors and Social Vulnerability. Arthritis Care Res (Hoboken). Published 10 January 2024. doi:10.1002/acr.25264

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