Diagnostic Accuracy Study of the Pediatric‐Specific Ultrasound Scoring System for the Knee Joint in Children With Juvenile Idiopathic Arthritis
Authors' conclusion
Our data indicate that the PAUSS-knee has excellent accuracy for the diagnosis of arthritis when compared with MRI.
Study context
- Population
- Children with juvenile idiopathic arthritis (JIA)80 children with JIA
- Participants
- 112 vs 25
- Comparison
- B-mode PAUSS-knee vs magnetic resonance imaging (MRI) as reference standard
- PAUSS-kneen = 112
- MRIn = 25reference
- Outcome
- Diagnostic accuracy of the PAUSS-knee for arthritis vs MRI as reference standard
Methodological detailsprospective
- Prospective
Performance
As reported in the abstract
Diagnosis of arthritis vs MRI
| Test or model | AUC (B-mode) | Sensitivity (cutoff >1) | Specificity (cutoff >1) |
|---|---|---|---|
| PAUSS-knee | 0.92 | 83% | 82% |
PAUSS-knee
AUC (B-mode)0.92
Sensitivity (cutoff >1)83%
Specificity (cutoff >1)82%
Further findings
Knees with clinical arthritis
- Knees with clinical evidence of arthritis
- 41% (n = 46)
Correlation of B-mode PAUSS-knee with clinical arthritis
- Rs (moderate), P < 0.001
- 0.54
Correlation of B-mode PAUSS-knee with Juvenile Arthritis MRI Scoring (JAMRIS) score
- Rs (strong), P < 0.001
- 0.75
Synovial fluid biomarkers
- IL-2R levels correlate with PAUSS score
Original publication
Diagnostic Accuracy Study of the Pediatric‐Specific Ultrasound Scoring System for the Knee Joint in Children With Juvenile Idiopathic Arthritis. Arthritis Care Res (Hoboken). Published 3 November 2023. doi:10.
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