Diagnosis of carpal tunnel syndrome with ultrasound: should we go more distal?

RMD OpenPublished Diagnostic accuracy study

Authors' conclusion

Adding the ultradistal level improves the performance of US for diagnosing CTS.

Study context

Population
Patients clinically diagnosed with primary carpal tunnel syndrome (CTS) and healthy controls219 patients and 39 controls
Comparison
Ultrasound (US) definitions of CTS vs clinical diagnosis
Outcome
Performance of US definitions of CTS (MN-CSA) vs clinical diagnosis
Methodological detailscase-control
  • Case-control

Performance

As reported in the abstract

Diagnostic performance vs clinical diagnosis (right hand)
Test or modelSensitivitySpecificity
Definition 398%95%
Definition 3 without ultradistal level90%— not stated in the abstract

Sensitivity

Definition 398%
Definition 3 without ultradistal level90%

Specificity

Definition 395%
Definition 3 without ultradistal level— not stated in the abstract

— not stated in the abstract

Further findings

OutcomePatientsControlsDifference (mm²)
MN-CSA, range across levelsMaximal at ultradistal level, right10.5-16.8 mm²6.2-7.6 mm²10.1
MN-CSA, range across levelsMaximal at ultradistal level, left8.3

Cross-sectional area (CSA) cut-offs (proximal, distal, ultradistal)

Right
11 mm², 9 mm² and 10 mm²
Left
10 mm², 8 mm² and 10 mm²

Original publication

Diagnosis of carpal tunnel syndrome with ultrasound: should we go more distal? RMD Open. Published 28 May 2025. doi:10.1136/rmdopen-2025-005563

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.