Pediatric rheumatology

Development of a mobile health application to support the management of paediatric FMF

Rheumatology (Oxford)Published Prospective before–after (pre–post) study

Authors' conclusion

Mobile reminder applications are low-cost, accessible digital health tools with strong potential to enhance medication adherence in FMF patients.

Study context

Population
Paediatric patients with FMF
Participants
93 patients
Exposure
Before vs after mobile reminder application use
Outcome
Medication adherence (MASIF scale)
Follow-up
3, 6 and 12 months
Methodological detailsmobile health application development, pilot testing in seven volunteer patients
  • Mobile health application development
  • Pilot testing in seven volunteer patients

Main finding

As reported in the abstract

Medication adherence (MASIF)

Before application use

44

median

P < 0.001

Observational data: associations, not effects.

Further findings

Disease activity (AIDAI) and attack frequency

AIDAI scores and attack frequency significantly decreased
No patient had an AIDAI score >9 during follow-up

Agreement between application-measured adherence and MASIF scores

ICC (excellent agreement)
> 0.90

Original publication

Development of a mobile health application to support the management of paediatric FMF. Rheumatology (Oxford). Published 3 June 2026. doi:10.1093/rheumatology/keag288

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