Lupus & antiphospholipid syndrome

Development and evaluation of frailty index for patients with systemic lupus erythematosus in China

LupusPublished Scale development and validation study

Authors' conclusion

The frailty index scale developed in this study is a valid and reliable tool for assessing frailty in SLE patients in China, with potential utility in clinical and research settings.

Study context

Population
Patients with systemic lupus erythematosus (SLE) in Chinapilot: 50 SLE patients
Outcome
Validity and reliability of the SLE frailty index scale
Methodological detailstwo-round Delphi expert consultation, pre-survey and formal survey
  • Two-round Delphi expert consultation
  • Pre-survey and formal survey

Performance

As reported in the abstract

Final scale items
14
Cronbach's α coefficient
0.809
Split-half reliability
0.745
KMO
0.820
Bartlett's test value
2915.855 (p < 0.001)
Overall correlation coefficient
0.832 (p < 0.001)
Item-dimension correlation coefficient, except for a few items
>0.4
Optimal cutoff, pre-frailty stage
28.5
Optimal cutoff, frailty stage
40.5

Further findings

Item reduction

Initial item pool: 3 dimensions, items
32
After two Delphi rounds: 3 dimensions, items
21

Original publication

Development and evaluation of frailty index for patients with systemic lupus erythematosus in China. Lupus. Published 4 April 2026. doi:10.1177/09612033261438992

Composed by AI from the published abstract and checked against it. How Briefs are made →

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