Rheumatoid arthritis

Determinants of health-related quality of life in adults living with rheumatoid arthritis: a systematic review

Semin Arthritis RheumPublished Systematic review

Authors' conclusion

HRQoL determinants were identified from multiple domains. The existing literature consists mostly of cross-sectional studies.

Study context

Population
Adults with rheumatoid arthritis (RA) in cross-sectional or prospective cohort studies published 2000 or later evaluating health-related quality of life (HRQoL) with SF-36/12/8/6D or EQ-5D21 studies
Outcome
HRQoL determinants identified by multivariable prediction models
Methodological detailsnarrative synthesis, cross-sectional or prospective cohort studies, multivariable prediction models, Three electronic databases searched; two authors conducted screening, data extraction and quality assessment
  • Narrative synthesis
  • Cross-sectional or prospective cohort studies
  • Multivariable prediction models
  • Three electronic databases searched; two authors conducted screening, data extraction and quality assessment

Pooled result

As reported in the abstract

HRQoL determinants

Determinants evaluated

70

Statistically significant HRQoL determinants

44

Domains: sociodemographic, RA-related, comorbidities and general health, health behaviours, psychosocial; RA-related most studied

5

Original publication

Determinants of health-related quality of life in adults living with rheumatoid arthritis: a systematic review. Semin Arthritis Rheum. Published 9 April 2025. doi:10.1016/j.semarthrit.2025.152717

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