Determinants of health-related quality of life in adults living with rheumatoid arthritis: a systematic review
Authors' conclusion
HRQoL determinants were identified from multiple domains. The existing literature consists mostly of cross-sectional studies.
Study context
- Population
- Adults with rheumatoid arthritis (RA) in cross-sectional or prospective cohort studies published 2000 or later evaluating health-related quality of life (HRQoL) with SF-36/12/8/6D or EQ-5D21 studies
- Outcome
- HRQoL determinants identified by multivariable prediction models
Methodological detailsnarrative synthesis, cross-sectional or prospective cohort studies, multivariable prediction models, Three electronic databases searched; two authors conducted screening, data extraction and quality assessment
- Narrative synthesis
- Cross-sectional or prospective cohort studies
- Multivariable prediction models
- Three electronic databases searched; two authors conducted screening, data extraction and quality assessment
Pooled result
As reported in the abstract
HRQoL determinants
Determinants evaluated
70
Statistically significant HRQoL determinants
44
Domains: sociodemographic, RA-related, comorbidities and general health, health behaviours, psychosocial; RA-related most studied
5
Original publication
Determinants of health-related quality of life in adults living with rheumatoid arthritis: a systematic review. Semin Arthritis Rheum. Published 9 April 2025. doi:10. 1016/ j. semarthrit. 2025. 152717
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