Depression, anxiety and cognitive function in persons with inflammatory rheumatic diseases: cross-sectional results from the German National Cohort (NAKO)
Authors' conclusion
Depression and anxiety are more frequent in iRMD compared with OA, whereas levels of cognitive dysfunction were comparable.
Study context
- Population
- Participants of the German National Cohort (NAKO), baseline databaseline data
- Participants
- 101,601 participants
- Exposure
- iRMD vs osteoarthritis (OA)
- iRMDn = 3,257
- OAn = 24,030reference
- Outcome
- Presence of mental health disorders (self-reported physician's diagnoses of depression and anxiety, Patient Health Questionnaire (PHQ-9), GAD-7, Mini-International Neuropsychiatric Interview (MINI) depression section) and cognitive tests
Methodological detailspopulation-based cohort, stratified by age and sex
- Population-based cohort
- Stratified by age and sex
Main finding
As reported in the abstract
Values
Physician's diagnosis of anxiety
Current depressive symptoms (PHQ-9 ≥10)
Anxiety symptoms (GAD-7 ≥10)
Observational data: associations, not effects.
Further findings
Cognitive function (neuropsychological tests, linear regression adjusted for sex and education)
- No differences in neuropsychological test results between iRMD and OA
Original publication
Depression, anxiety and cognitive function in persons with inflammatory rheumatic diseases: cross-sectional results from the German National Cohort (NAKO). RMD Open. Published 23 October 2024. doi:10.
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