Osteoarthritis

Cost‐Effectiveness of Community‐Based Diet and Exercise for Patients with Knee Osteoarthritis and Obesity or Overweight

Arthritis Care Res (Hoboken)Published Cost-effectiveness analysis

Authors' conclusion

The community-based D + E program for persons with knee OA and BMI >27kg/m2 could be cost-effective for willingness-to-pay thresholds greater than $62,000/QALY.

Study context

Population
Simulated cohort with knee osteoarthritis (OA) and body mass index (BMI) >27 kg/m² (mean age 65 years, BMI 37 kg/m², WOMAC pain 38 on 0–100)
Comparison
Usual care (UC) vs UC + health education (HE) vs UC + (D + E), each vs next-best strategy by increasing lifetime cost
Outcome
QALYs, cost and incremental cost-effectiveness ratios (ICERs)
Follow-up
Lifetime
Methodological detailsmodel-based, Osteoarthritis Policy Model, lifetime horizon, societal perspective, inputs from the WE-CAN trial
  • Model-based
  • Osteoarthritis Policy Model
  • Lifetime horizon
  • Societal perspective
  • Inputs from the WE-CAN trial

Main finding

As reported in the abstract

GroupValueLifetime costICER (societal)
UC9.36 quality-adjusted life years (QALYs)/person$147,102
UC + HE9.44 QALYs$148,139$12,700/QALY
UC + (D + E)9.49 QALYS$151,478$61,700/QALY

Value

UC9.36 QALYs/person
UC + HE9.44 QALYs
UC + (D + E)9.49 QALYS

Lifetime cost

UC$147,102
UC + HE$148,139
UC + (D + E)$151,478

ICER (societal)

UC— not stated in the abstract
UC + HE$12,700/QALY
UC + (D + E)$61,700/QALY

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Cost‐Effectiveness of Community‐Based Diet and Exercise for Patients with Knee Osteoarthritis and Obesity or Overweight. Arthritis Care Res (Hoboken). Published 22 March 2024. doi:10.1002/acr.25323

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