Association of Muscle Quality and Pain in Adults With Symptomatic Knee Osteoarthritis, Independent of Muscle Strength: Findings From a Cross‐Sectional Study
Authors' conclusion
These preliminary findings suggest that EI and SWV may impact knee OA pain and could serve as malleable treatment targets.
Study context
- Population
- Adults (age >50 years) meeting clinical criteria for knee osteoarthritis (OA)
- Participants
- 26 adults
- Outcome
- Associations between muscle quality (EI and SWV of the rectus femoris, quantitative US) and pain, controlling for strength, age, sex and BMI
Main finding
As reported in the abstract
Associations of muscle quality with pain (multiple linear regression)
EI and SWV with movement-evoked pain, b
0.452-0.839
P = 0.024-0.029
SWV with clinical pain intensity, b
0.45
P = 0.034
SWV with pressure pain threshold at medial index knee joint line, b (adjusted for all covariates)
−0.41
P = 0.025
SWV with pressure pain threshold at lateral index knee joint line, b (adjusted for all covariates)
−0.54
P = 0.009
Observational data: associations, not effects.
Further findings
- Knee extension strength with pain interference, b
- −0.51 (P = 0.041)
Original publication
Association of Muscle Quality and Pain in Adults With Symptomatic Knee Osteoarthritis, Independent of Muscle Strength: Findings From a Cross‐Sectional Study. Arthritis Rheumatol. Published 19 March 2024. doi:10.
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