Vasculitis & polymyalgia rheumatica

Corticosteroids reduce vascular ultrasound sensitivity in fast- track pathways (FTP): results from Coventry Multi-Disciplinary FTP for cranial Giant Cell Arteritis

Scand J RheumatolPublished Retrospective cohort study

Authors' conclusion

This novel multidisciplinary pathway demonstrates excellent feasibility and minimizes the use of CSs in patients without giant cell arteritis.

Study context

Population
Patients attending the Coventry multidisciplinary fast-track cranial GCA pathway, 1 January 2014 to 31 December 2017
Participants
620 patients
Exposure
Ultrasound (US) performance in corticosteroid (CS)-naïve patients vs patients with prior CS use
Outcome
Feasibility of the FTGCA pathway and impact of prior CS use on US performance
Methodological detailsmultidisciplinary fast-track pathway, real-life
  • Multidisciplinary fast-track pathway
  • Real-life

Main finding

As reported in the abstract

Diagnostic performance of US for cranial GCA
GroupSensitivity
CS-naïvenearly 56%
Prior CSaround 46%

Sensitivity

CS-naïvenearly 56%
Prior CSaround 46%
US sensitivity, overall
50%
US specificity, overall
> 96%

Observational data: associations, not effects.

Further findings

OutcomePrior CS
Duration of CS use prior to USmedian 2 days

CS use avoided completely

Patients in whom CS use was avoided completely
345 (56%)

Original publication

Corticosteroids reduce vascular ultrasound sensitivity in fast- track pathways (FTP): results from Coventry Multi-Disciplinary FTP for cranial Giant Cell Arteritis. Scand J Rheumatol. Published 20 April 2022. doi:10.1080/03009742.2022.2051279

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