Vasculitis & polymyalgia rheumatica
Coronary artery disease in Behçet’s syndrome: a coronary computed tomography angiography study
Authors' conclusion
BS does not appear to accelerate atherosclerosis, in contrast to other systemic rheumatic diseases.
Study context
- Population
- Asymptomatic male Behçet's syndrome (BS) patients and matched male controls
- Participants
- 178 vs 139
- Exposure
- Asymptomatic male BS patients vs matched male controls
- BSn = 178
- Controlsn = 139reference
- Outcome
- Coronary artery involvement on CCTA (stenosis, aneurysm, arteritis or occlusion)
Methodological detailsmatched controls, coronary CT angiography, coronary CT angiography (CCTA) images evaluated independently by two radiologists, excellent inter-observer agreement
- Matched controls
- Coronary CT angiography
- CCTA images evaluated independently by two radiologists, excellent inter-observer agreement
Main finding
As reported in the abstract
Any coronary lesion prevalence
P = 0.694
Observational data: associations, not effects.
Further findings
| Outcome | BS | P value |
|---|---|---|
| Stenosis | 20.8% | P = 0.286 |
| Vasculitis-related lesions (aneurysm, arteritis, total occlusion) | ||
| Aneurysms | 5.1% | |
| Arteritis | 4.0% | |
| Total occlusions | 1.7% |
Agatston calcium scores
- Similar between BS patients and controls
Vasculitis-related lesions (aneurysm, arteritis, total occlusion)
- Occurred only in BS patients
Predictors of any coronary lesion
- Age, OR (95% CI 1.047-1.184, P < 0.001), independent predictor
- 1.113
- Venous involvement, OR (95% CI 0.114-0.664, P = 0.004), protective association
- 0.275
Clinical risk stratification
- Arterial and neurological involvement highest risk; venous involvement lowest risk
Original publication
Coronary artery disease in Behçet’s syndrome: a coronary computed tomography angiography study. Rheumatology (Oxford). Published 17 October 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →