Construct validity of the PROMIS PF-10 in patients with inflammatory rheumatic diseases and severe limitations in physical functioning
Authors' conclusion
The overall strong correlation of the PROMIS PF-10 with measures of PF and moderate to weak correlations with outcomes measuring different constructs were confirmed in subpopulations of RA and axSpA patients with severe functional limitations, supporting its construct validity.
Study context
- Population
- Rheumatoid arthritis (RA) or axial spondyloarthritis (axSpA) patients with severe limitations in physical functioninganalysed
- Participants
- 316 participants
- Exposure
- RA vs axSpA
- RAn = 180
- axSpAn = 136
- Outcome
- Construct validity of PROMIS PF-10: correlations with measures of physical functioning and quality of life (hypothesis testing)
Methodological detailsconstruct validity, hypothesis testing
- Construct validity
- Hypothesis testing
Main finding
As reported in the abstract
Correlations of PROMIS PF-10 with other measures
Strong correlation with HAQ-DI, BASFI and EQ-5D-5L index score
r > 0.6
Moderate correlation with SF-36 Physical Component Summary, EQ-VAS and 6MWT
0.30 ≤ r ≤ 0.60
Weak correlation with SF-36 Mental Component Summary
r < 0.30
Hypotheses confirmed in both groups
Five of six hypotheses (83%)
Observational data: associations, not effects.
Further findings
Median
| Outcome | RA | axSpA |
|---|---|---|
| PROMIS PF-10 score | 34.5 (IQR 31.4–37.6) | 36.0 (IQR 32.8–38.3) |
Original publication
Construct validity of the PROMIS PF-10 in patients with inflammatory rheumatic diseases and severe limitations in physical functioning. Scand J Rheumatol. Published 20 March 2023. doi:10.
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