Conflicts of Interest Reporting in Trials and Guidelines Addressing Glucocorticoid Injections for Knee Osteoarthritis
Authors' conclusion
Conflict of interest reporting practices in trials and guidelines assessing effectiveness of glucocorticoid injections for knee osteoarthritis are poor, with a lack of transparency.
Study context
- Population
- RCTs (database inception to April 2025) and clinical practice guidelines addressing GC injections for knee OA
- Participants
- 75 vs 14
- Exposure
- Trials vs guidelines
- Trialsn = 75
- Guidelinesn = 14
- Outcome
- Conflict of interest disclosure practices (transparency and appropriateness of disclosures; discrepancies with public databases)
Methodological detailsmeta-research of RCTs and clinical practice guidelines, comparison with three national public conflict of interest disclosure databases, CINAHL, Ovid MEDLINE ALL and Embase searched from inception to April 2025
- Meta-research of RCTs and clinical practice guidelines
- Comparison with three national public conflict of interest disclosure databases
- CINAHL, Ovid MEDLINE ALL and Embase searched from inception to April 2025
Main finding
As reported in the abstract
No conflict of interest statement
Trials
Twenty-nine percent
22 of 75
Guidelines
14.3%
2 of 14
Observational data: associations, not effects.
Further findings
Conflict of interest reported for at least one author
Articles with discrepancies between disclosures in articles and public databases
Authors with discrepancies between disclosures in articles and public databases · counts are authors, not articles
Original publication
Conflicts of Interest Reporting in Trials and Guidelines Addressing Glucocorticoid Injections for Knee Osteoarthritis. Arthritis Care Res (Hoboken). Published 18 March 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →