Association of Wearable Sensor–Derived Gait Measures With Cartilage Damage Over Two Years Among Adults With or at Risk of Knee Osteoarthritis
Authors' conclusion
Longer step length was associated with worse cartilage damage over two years.
Study context
- Population
- Adults aged 45 to 90 years with, or at risk for, knee osteoarthritis (OA) from the Multicenter Osteoarthritis Study (MOST)56% female
- Participants
- 1,703 adults
- Outcome
- Cartilage damage worsening (MRI Osteoarthritis Knee Scores) in 14 knee subregions
- Follow-up
- Two years
Methodological detailsmulticentre, ensemble machine learning, G-computation, 70% training / 30% test split, Gait assessed with inertial measurement units on pelvis and ankles during a 20-m walk; knee magnetic resonance imaging (MRI) at baseline and two years
- Multicentre
- Ensemble machine learning
- G-computation
- 70% training / 30% test split
- Gait assessed with inertial measurement units on pelvis and ankles during a 20-m walk; knee MRI at baseline and two years
Main finding
As reported in the abstract
Worse cartilage damage in at least one knee subregion
Participants with worse cartilage damage in at least one knee subregion
46%
Observational data: associations, not effects.
Original publication
Association of Wearable Sensor–Derived Gait Measures With Cartilage Damage Over Two Years Among Adults With or at Risk of Knee Osteoarthritis. Arthritis Care Res (Hoboken). Published 13 March 2026. doi:10. 1002/ acr. 80018
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