Osteoarthritis

Association of Wearable Sensor–Derived Gait Measures With Cartilage Damage Over Two Years Among Adults With or at Risk of Knee Osteoarthritis

Arthritis Care Res (Hoboken)Published Prospective cohort study

Authors' conclusion

Longer step length was associated with worse cartilage damage over two years.

Study context

Population
Adults aged 45 to 90 years with, or at risk for, knee osteoarthritis (OA) from the Multicenter Osteoarthritis Study (MOST)56% female
Participants
1,703 adults
Outcome
Cartilage damage worsening (MRI Osteoarthritis Knee Scores) in 14 knee subregions
Follow-up
Two years
Methodological detailsmulticentre, ensemble machine learning, G-computation, 70% training / 30% test split, Gait assessed with inertial measurement units on pelvis and ankles during a 20-m walk; knee magnetic resonance imaging (MRI) at baseline and two years
  • Multicentre
  • Ensemble machine learning
  • G-computation
  • 70% training / 30% test split
  • Gait assessed with inertial measurement units on pelvis and ankles during a 20-m walk; knee MRI at baseline and two years

Main finding

As reported in the abstract

Worse cartilage damage in at least one knee subregion

Participants with worse cartilage damage in at least one knee subregion

46%

Observational data: associations, not effects.

Original publication

Association of Wearable Sensor–Derived Gait Measures With Cartilage Damage Over Two Years Among Adults With or at Risk of Knee Osteoarthritis. Arthritis Care Res (Hoboken). Published 13 March 2026. doi:10.1002/acr.80018

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