A comprehensive analysis of trends and inequalities in rheumatoid arthritis burden among women of childbearing age: insights from the Global Burden of Disease study 2021
Authors' conclusion
The RA burden among WCBA has significantly increased over the past 32 years, with a notable shift in risk towards younger populations. Higher SDI regions bore a disproportionately greater burden.
Study context
- Population
- Women of childbearing age with rheumatoid arthritis (RA), global, regional and national levels, 1990–2021
- Outcome
- RA prevalence, incidence, DALYs and deaths among women of childbearing age, trends and inequalities
- Follow-up
- 2021
Methodological detailsGlobal Burden of Disease Study 2021 data, percentage change, estimated annual percentage change (EAPC), ARIMA projection to 2050
- Global Burden of Disease Study 2021 data
- Percentage change
- EAPC
- ARIMA projection to 2050
Main finding
As reported in the abstract
Global RA burden among women of childbearing age
- Prevalent cases
- 4.45 million
- Incident cases
- 326.6 thousand
- Disability-adjusted life years (DALYs) cases
- 650.75 thousand
- Percentage change since 1990, prevalence
- 88%
- Percentage change since 1990, incidence
- 68%
- Percentage change since 1990, DALYs
- 71%
- EAPC prevalence rate
- 0.89 (95% UI 0.87-0.92)
- EAPC incidence rate
- 0.54 (95% UI 0.51-0.56)
- EAPC DALYs rate
- 0.61 (95% UI 0.57-0.64)
Observational data: associations, not effects.
Further findings
Deaths
- Death cases and rates decreased globally and in most regions
Burden by Socio-Demographic Index (SDI) region
- High SDI region reported the highest rates of RA burden
Incidence by age · 2021
- Age 45-49, highest incidence: cases
- 59.22 thousand
- Age 45-49, incidence rate per 10,000
- 25.13
- Age 15-19, fastest incidence growth (EAPC)
- 0.64
Projection to 2050
- Prevalence rate per 100,000
- 266.34
- DALYs rate per 100,000
- 37.63
- Incidence will stabilise and deaths continue to decline
- ARIMA model
Original publication
A comprehensive analysis of trends and inequalities in rheumatoid arthritis burden among women of childbearing age: insights from the Global Burden of Disease study 2021. Clin Exp Rheumatol. Published 24 December 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →