Sjögren's disease & overlap diseases
Complications after minor salivary gland biopsy: a retrospective study of 630 patients from two Swedish centres
Authors' conclusion
A high frequency of long-standing impaired sensation after MSGB was found among patients who had undergone MSGB, although it had a low impact on everyday life. The complication frequency was less pronounced when a dentist or an OMS had performed the biopsy.
Study context
- Population
- Patients who had undergone minor salivary gland biopsy (MSGB) between 2007 and 2016 at two Swedish centres
- Participants
- 630 patients
- Exposure
- MSGB performed by rheumatologists vs by dentists or OMSs
- Karolinska University Hospital (KUH)n = 505
- Skåne University Hospital (SUH)n = 125reference
- Outcome
- Prevalence of impaired sensation after MSGB
Methodological detailsquestionnaire survey, medical record review, two-centre
- Questionnaire survey
- Medical record review
- Two-centre
Main finding
As reported in the abstract
- Reported by 21% of patients; associated with lower age and absence of anti-SSA antibodies
Observational data: associations, not effects.
Further findings
Long-standing impaired sensation by centre · significantly lower frequency in SUH
P = 0.02
Inconvenience of impaired sensation (1-10), patients with long-standing impaired sensation
- Inconvenience (1-10), median (IQR)
- 4.0 (2.0-7.0)
Influence on quality of life (QoL), patients with long-standing impaired sensation
- Reported an influence on QoL
- 32%
Influence on everyday life (1-10), patients with long-standing impaired sensation
- Influence on everyday life (1-10), median (IQR)
- 3.0 (1.0-5.0)
Original publication
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