Spondyloarthritis & psoriatic arthritis
Comparison of radiographic spinal changes and their progression in patients with axial spondyloarthritis vs. psoriatic arthritis with inflammatory axial involvement
Main finding · Estimated mean progression in mSASSSResult — go to the resultAdjusted β −0.088 95% CI −0.446 to 0.271Authors' conclusion
Patients with PsA-ax were found to have slightly lower mean progression in mSASSS over two years than patients with axSpA.
Study context
- Population
- Patients with axial spondyloarthritis (axSpA) or PsA-ax with lateral radiographs of the cervical, thoracic and/or lumbar spine
- Participants
- 246 patients
- Exposure
- PsA with inflammatory axial involvement vs axSpA
- PsA-axn = 74
- axSpAn = 172reference
- Outcome
- Radiographic spinal progression (modified Stoke Ankylosing Spondylitis Spinal Score (mSASSS))
- Follow-up
- 2 years
Methodological detailsadjusted linear mixed-effects model
- Adjusted linear mixed-effects model
Main finding
Estimated mean progression in mSASSS · two years
Adjusted β
−0.088
95% CI −0.446 to 0.271
As reported in the abstract
Observational data: associations, not effects.
Further findings
Patient-level mean mSASSS change >0 units · 2 years
| Outcome | PsA-ax | axSpA |
|---|---|---|
| Patient-level mean mSASSS change · 2 years | 0.07 (SD 0.29) | 0.39 (SD 1.83) |
| Baseline mSASSSAveraging | 0.96 (SD 2.12) | 6 (SD 14) |
Original publication
Comparison of radiographic spinal changes and their progression in patients with axial spondyloarthritis vs. psoriatic arthritis with inflammatory axial involvement. Arthritis Res Ther. Published 19 December 2025. doi:10. 1186/ s13075-025-03692-8
Composed by AI from the published abstract and checked against it. How Briefs are made →