Spondyloarthritis & psoriatic arthritis

Comparison of radiographic spinal changes and their progression in patients with axial spondyloarthritis vs. psoriatic arthritis with inflammatory axial involvement

Arthritis Res TherPublished Retrospective cohort study

Main finding · Estimated mean progression in mSASSSResult — go to the resultAdjusted β −0.088 95% CI −0.446 to 0.271

Authors' conclusion

Patients with PsA-ax were found to have slightly lower mean progression in mSASSS over two years than patients with axSpA.

Study context

Population
Patients with axial spondyloarthritis (axSpA) or PsA-ax with lateral radiographs of the cervical, thoracic and/or lumbar spine
Participants
246 patients
Exposure
PsA with inflammatory axial involvement vs axSpA
  • PsA-axn = 74
  • axSpAn = 172reference
Outcome
Radiographic spinal progression (modified Stoke Ankylosing Spondylitis Spinal Score (mSASSS))
Follow-up
2 years
Methodological detailsadjusted linear mixed-effects model
  • Adjusted linear mixed-effects model

Main finding

Estimated mean progression in mSASSS · two years

Adjusted β

−0.088

95% CI −0.446 to 0.271

As reported in the abstract

Observational data: associations, not effects.

Further findings

Patient-level mean mSASSS change >0 units · 2 years

OutcomePsA-axaxSpA
Patient-level mean mSASSS change · 2 years0.07 (SD 0.29)0.39 (SD 1.83)
Baseline mSASSSAveraging0.96 (SD 2.12)6 (SD 14)

Original publication

Comparison of radiographic spinal changes and their progression in patients with axial spondyloarthritis vs. psoriatic arthritis with inflammatory axial involvement. Arthritis Res Ther. Published 19 December 2025. doi:10.1186/s13075-025-03692-8

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.