Spondyloarthritis & psoriatic arthritis
Comparison of established and preliminarily proposed ASAS MRI working group cut-offs for inflammatory MRI lesions in the sacroiliac joints in radiographic and non-radiographic axial spondyloarthritis
Authors' conclusion
This analysis suggests that the preliminary 2021 cut-offs for MRI inflammatory lesions may slightly increase the specificity of the quantitative part of the 2009 MRI inflammatory lesion definition.
Study context
- Population
- Axial spondyloarthritis (axSpA) (radiographic and non-radiographic) patients treated with certolizumab pegol
- Participants
- 657 participants
- Comparison
- 2009 vs preliminary 2021 ASAS MRI inflammatory cut-offs for MRI+/MRI- classification, by clinical outcomes on certolizumab pegol
- Discordantn = 53
Primary result
As reported in the abstract
Clinical outcomes (ASAS40, ASDAS, BASDAI) by MRI cut-off subgroup · to week 48
Discordant
8.1%
53
Original publication
Comparison of established and preliminarily proposed ASAS MRI working group cut-offs for inflammatory MRI lesions in the sacroiliac joints in radiographic and non-radiographic axial spondyloarthritis. RMD Open. Published 3 September 2024. doi:10. 1136/ rmdopen-2023-003886
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