Systemic sclerosis & Raynaud's
Colour changes in the feet: a sign of autonomic symptoms in systemic sclerosis
Authors' conclusion
Dependent extremity discolouration is common in dysautonomia. Patients with SSc who report colour changes in their feet are more likely to report other symptoms of autonomic dysfunction.
Study context
- Population
- Patients with SSc completing the COMPASS-31 survey; POTS patients for comparisonSSc
- Participants
- 167 patients
- Exposure
- SSc patients with vs without foot discolouration; POTS patients for comparison
- POTSn = 79
- Outcome
- COMPASS-31 autonomic symptom subdomain scores (orthostatic, gastrointestinal (GI), urinary, secretomotor, pupillomotor) in SSc with vs without foot discolouration
Methodological detailsmultivariable model adjusting for potential confounders
- Multivariable model adjusting for potential confounders
Main finding
As reported in the abstract
COMPASS-31 subdomain scores
SSc patients reporting colour changes in their feet
62%
Observational data: associations, not effects.
Further findings
Site of extremity discolouration
- Extremity discolouration common in POTS and more often affects the feet; in SSc the hands are more frequently involved
Original publication
Colour changes in the feet: a sign of autonomic symptoms in systemic sclerosis. Rheumatology (Oxford). Published 20 September 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →