Lupus & antiphospholipid syndrome
Childhood adverse experiences and clinical manifestations in women with systemic lupus erythematosus
Authors' conclusion
Individuals with a positive history of ACE have significant associations with certain clinical manifestations of SLE and subtypes of ACE
Study context
- Population
- Adult women diagnosed with SLE
- Participants
- 97 women
- Exposure
- ACE subtypes vs clinical manifestations of SLE
- Outcome
- Association of ACE (CTQ) with clinical manifestations of SLE
Methodological detailsobservational, analytical, Data collected through interviews and a review of medical records
- Observational
- Analytical
- Data collected through interviews and a review of medical records
Main finding
As reported in the abstract
Significant associations between ACE subtypes and SLE manifestations
- Physical abuse and oral ulcers
- p = .006
- Physical abuse and nephritis
- p = .032
- Sexual abuse and Sjogren's syndrome
- p = .024
- Sexual abuse and oral ulcers
- p = .035
- Physical neglect and photosensitivity
- p = .024
- Physical neglect and oral ulcers
- p = .039
- Emotional neglect and diabetes mellitus
- p = .033
Observational data: associations, not effects.
Original publication
Childhood adverse experiences and clinical manifestations in women with systemic lupus erythematosus. Lupus. Published 8 March 2024. doi:10. 1177/ 09612033241238056
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