Lupus & antiphospholipid syndrome

Childhood adverse experiences and clinical manifestations in women with systemic lupus erythematosus

LupusPublished Cross-sectional study

Authors' conclusion

Individuals with a positive history of ACE have significant associations with certain clinical manifestations of SLE and subtypes of ACE

Study context

Population
Adult women diagnosed with SLE
Participants
97 women
Exposure
ACE subtypes vs clinical manifestations of SLE
Outcome
Association of ACE (CTQ) with clinical manifestations of SLE
Methodological detailsobservational, analytical, Data collected through interviews and a review of medical records
  • Observational
  • Analytical
  • Data collected through interviews and a review of medical records

Main finding

As reported in the abstract

Significant associations between ACE subtypes and SLE manifestations
Physical abuse and oral ulcers
p = .006
Physical abuse and nephritis
p = .032
Sexual abuse and Sjogren's syndrome
p = .024
Sexual abuse and oral ulcers
p = .035
Physical neglect and photosensitivity
p = .024
Physical neglect and oral ulcers
p = .039
Emotional neglect and diabetes mellitus
p = .033

Observational data: associations, not effects.

Original publication

Childhood adverse experiences and clinical manifestations in women with systemic lupus erythematosus. Lupus. Published 8 March 2024. doi:10.1177/09612033241238056

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