Pediatric rheumatology

Characteristics of juvenile idiopathic arthritis (JIA)-associated uveitis at the age of transition

Pediatr Rheumatol Online JPublished Retrospective cohort study

Authors' conclusion

This study highlights the substantial burden of JIA-associated uveitis at the time of transition to adult care, characterized by frequent complications, persistent disease activity, and a high need for biologic therapy.

Study context

Population
Patients with JIA and past or present uveitis who transitioned to adult rheumatology at Cochin Hospital, 2016–2024
Participants
46 patients
Outcome
Ophthalmologic and rheumatologic disease characteristics at transition from pediatric to adult care
Follow-up
Transition to adult care
Methodological detailssingle-centre, descriptive
  • Single-centre
  • Descriptive

Main finding

As reported in the abstract

Disease characteristics at transition
Median age at JIA diagnosis, years [IQR 2.0-16.0]
7.5
Median age at first uveitis, years [IQR 3.0-12.2]
6.0
Median follow-up after transition, years [IQR 1.17-3.94]
2.44
Female (n = 37)
80%
Oligoarticular JIA (n = 27)
59%
Chronic uveitis (n = 38)
83%
Ocular complications (n = 17)
46%
Cataract (n = 11)
24%
Glaucoma (n = 9)
20%
Keratitis (n = 3)
7%
≥ 5 flares since diagnosis (n = 13/23)
57%
bDMARD prescribed, predominantly TNFi (n = 23/43)
53%

Observational data: associations, not effects.

Original publication

Characteristics of JIA-associated uveitis at the age of transition. Pediatr Rheumatol Online J. Published 19 May 2026. doi:10.1186/s12969-026-01217-4

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