Lupus & antiphospholipid syndrome
Characteristics and outcomes of a Hispanic lupus nephritis cohort from Mexico
Authors' conclusion
Although the response to treatment and patient survival in this Latin American cohort is comparable to that observed in other regions, there is still a high rate of renal relapses and progression to decline in kidney function.
Study context
- Population
- Hispanic patients from Mexico with SLE and biopsy-proven LN followed for >36 months96% female
- Participants
- 440 patients
- Outcome
- Complete response to therapy (cumulative rate)
- Follow-up
- 6, 12 and 24 months
Methodological detailssurvival analysis
- Survival analysis
Main finding
As reported in the abstract
Complete response at 6 months
22.3%
Complete response at 12 months
40.5%
Complete response at 24 months
51.6%
Observational data: associations, not effects.
Further findings
Factors associated with loss of kidney function
- Age, eGFR at presentation, histologic chronicity index in the kidney biopsy, and type of response to therapy
Original publication
Characteristics and outcomes of a Hispanic lupus nephritis cohort from Mexico. Rheumatology (Oxford). Published 13 July 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →