Spondyloarthritis & psoriatic arthritis
Central Sensitization in Psoriatic Arthritis: Relationship With Composite Measures of Disease Activity, Functional Disability, and Health-Related Quality of Life
Authors' conclusion
Patients with PsA with symptoms of CS had higher disease activity, worse functional ability, and worse QOL. The presence of CS is the major contributor in the impact of disease.
Study context
- Population
- Adults with PsA without coexisting fibromyalgia (FM)
- Participants
- 157 adults
- Outcome
- Prevalence of central sensitization (CSI ≥ 40)
Main finding
As reported in the abstract
High probability of central sensitization (CS) (CSI ≥ 40)
Patients scoring CS Inventory (CSI) ≥ 40
45.2%
Observational data: associations, not effects.
Further findings
Correlation of CSI with disease activity, function and quality of life (QOL) (Spearman ρ)
ρ
- CSI vs DAPSA
- 0.587
- CSI vs PASDAS
- 0.573
- CSI vs HAQ
- 0.607
- CSI vs SF-36 physical component summary
- −0.405
- CSI vs SF-36 mental component summary
- −0.483
Independent contributors to Psoriatic Arthritis Impact of Disease (PsAID-12) score (multivariate analysis)
- CSI score principal independent variable
- P < 0.001
Original publication
Central Sensitization in Psoriatic Arthritis: Relationship With Composite Measures of Disease Activity, Functional Disability, and Health-Related Quality of Life. J Rheumatol. Published 15 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →