Systemic sclerosis & Raynaud's

Causes and predictors of death among Finnish patients with systemic sclerosis

Scand J RheumatolPublished Retrospective cohort study

Authors' conclusion

The disease itself was the major cause of death among Finnish SSc patients, in both diffuse and limited forms of SSc.

Study context

Population
Finnish patients with systemic sclerosis (SSc) (ICD-10 code M34) registered 1996–2018 in two university hospitals91 deaths
Participants
313 patients
Exposure
Died of SSc vs Died of other causes
Outcome
Causes and predictors of death
Methodological detailstwo university hospitals
  • Two university hospitals

Main finding

As reported in the abstract

Causes of death

SSc was the most common primary cause of death (n)

35

Interstitial lung disease (ILD) was the most common SSc-related cause of death (n)

13

Diffuse SSc patients who died as a result of SSc itself

52%

Limited cutaneous SSc patients who died as a result of SSc itself

33%

Observational data: associations, not effects.

Further findings

Age at death · significantly younger

P = 0.0006

95% CI Died of SSc 61.2-70.1 · Died of other causes 71.5-76.9

Overall survival · 5 and 10 years

5-year survival rate
88.4%
10-year survival rate
80.2%

Original publication

Causes and predictors of death among Finnish patients with systemic sclerosis. Scand J Rheumatol. Published 14 May 2024. doi:10.1080/03009742.2024.2335781

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