Cardiovascular events in patients with myositis: results from a French retrospective cohort
Authors' conclusion
Patients with cardiac involvement at myositis diagnosis are at increased risk of CVE and experience them earlier than patients without and should be carefully followed up, particularly during the first months after diagnosis.
Study context
- Population
- Patients with idiopathic inflammatory myositis (IIM) (dermatomyositis (DM), inclusion body myositis (IBM), immune-mediated necrotising myopathy (IMNM), antisynthetase syndrome, overlap myositis), Saint Antoine University Hospital, Paris, 1997–2020median age 49 years
- Participants
- 78 patients
- Exposure
- Cardiac involvement at diagnosis vs no cardiac involvement at diagnosis
- Cardiac involvementn = 12
- Outcome
- CVE: HF due to ischaemia, arrhythmia or conductive block, inflammatory myocarditis or resuscitation department admission
Methodological detailssingle-centre, observational
- Single-centre
- Observational
Main finding
As reported in the abstract
CVE during follow-up
P = 0.01
- Cardiovascular events (CVE) during follow-up, whole cohort
- 15 (19%)
Observational data: associations, not effects.
Further findings
Time to CVE
P < 0.01
Cardiac involvement at diagnosis (prevalence)
- Cardiac involvement at diagnosis
- 12 (15%)
Original publication
Cardiovascular events in patients with myositis: results from a French retrospective cohort. RMD Open. Published 12 March 2025. doi:10.
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