Rheumatoid arthritis

Breastfeeding determinants in Egyptian mothers with systemic lupus erythematosus or rheumatoid arthritis: a retrospective cohort study

Lupus Sci MedPublished Retrospective cohort study

Authors' conclusion

Breastfeeding is significantly less prevalent among Egyptian mothers with SLE and RA when compared with control group.

Study context

Population
Egyptian mothers with systemic lupus erythematosus (SLE) or rheumatoid arthritis (RA) and healthy mothers
Participants
320 pregnancies
Exposure
Mothers with SLE vs RA vs healthy mothers
  • SLEn = 62
  • RAn = 71
  • Controlsn = 59reference
Outcome
Breastfeeding initiation, duration and predictors of early discontinuation (<6 months post partum)
Methodological detailsmulticentre
  • Multicentre

Main finding

As reported in the abstract

Exclusive breastfeeding

P < 0.001

Observational data: associations, not effects.

Further findings

Breastfeeding continuation beyond 6 months — SLE vs Controls · SLE and RA vs controls

P < 0.001

OutcomeaOR (95% CI)
Postpartum depression as predictor of discontinuationSLEvs ControlsWithin SLE0.06 (0.01–0.6)
Postpartum depression as predictor of discontinuationRAvs ControlsWithin RA0.34 (0.13–0.9)
OutcomeaORP value
Breastfeeding odds (multivariable GEE)SLE vs Controls0.41P = 0.040

Original publication

Breastfeeding determinants in Egyptian mothers with systemic lupus erythematosus or rheumatoid arthritis: a retrospective cohort study. Lupus Sci Med. Published 22 September 2025. doi:10.1136/lupus-2025-001733

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