Systemic sclerosis & Raynaud's
Body composition parameters in systemic sclerosis—a systematic review and meta-analysis
Authors' conclusion
Altered BC is characteristic of SSc patients
Study context
- Population
- Studies with body composition (BC) data by DXA or bioelectrical impedance analysis (BIA) in patients with SSc and healthy controls9 studies
- Participants
- 489 vs 404
- Comparison
- SSc patients vs healthy controls
- SScn = 489
- Healthy controls (HC)n = 404reference
- Outcome
- Body composition (BMI, lean mass, fat mass, phase angle) by DXA or BIA, as MD
Methodological detailsrandom-effects meta-analysis, Newcastle-Ottawa scale risk of bias, Databases searched 4 January 2023: Web of Science, PubMed, Scopus, Cochrane Library; 593 publications retrieved
- Random-effects meta-analysis
- Newcastle-Ottawa scale risk of bias
- Databases searched 4 January 2023: Web of Science, PubMed, Scopus, Cochrane Library; 593 publications retrieved
Pooled result
As reported in the abstract
Body composition, SSc vs HC
- Significantly lower BMI, lean mass, fat mass and phase angle in SSc vs HC
Further pooled results
Fat mass and lean mass by measurement method (subgroup)
- Fat mass (FM) and lean mass (LM) significantly lower in SSc when DXA applied
- FM and LM comparable between groups when BIA applied
Original publication
Body composition parameters in systemic sclerosis—a systematic review and meta-analysis. Rheumatology (Oxford). Published 30 August 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →