Vasculitis & polymyalgia rheumatica

Biologics in peripheral ulcerative keratitis

Semin Arthritis RheumPublished Literature review

Authors' conclusion

Overall, whilst the evidence base for biologic use in PUK was poor, reported cases demonstrate an increasingly powerful and effective role for biologics in refractory PUK.

Study context

Population
Patients with peripheral ulcerative keratitis (PUK) treated with a biologic, reported in peer-reviewed articles (Medline, Embase, Cochrane Database of Systematic Reviews)
Methodological detailsLiterature search across Medline, Embase and Cochrane Database of Systematic Reviews
  • Literature search across Medline, Embase and Cochrane Database of Systematic Reviews

Main finding

As reported in the abstract

  • Evidence base for biologic use in PUK poor; reported cases show an increasingly powerful and effective role for biologics in refractory PUK
  • Particularly RTX in PUK secondary to GPA

Original publication

Biologics in peripheral ulcerative keratitis. Semin Arthritis Rheum. Published 26 September 2023. doi:10.1016/j.semarthrit.2023.152269

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