Lupus & antiphospholipid syndrome

Benefits & risks of physical activity in patients with Systemic Lupus Erythematosus: a systematic review of the literature

Semin Arthritis RheumPublished Systematic review

Authors' conclusion

Aerobic and resistance training programs had clear benefits and were well tolerated in SLE patients with stable disease.

Study context

Population
Patients with Systemic Lupus Erythematosus (SLE); articles published 1989–202240 articles
Participants
2,291 patients
Outcome
Benefits and potential risks of PA in SLE
Methodological detailsMEDLINE (via PubMed) from inception to March 2022, two authors independently assessed studies and extracted data
  • MEDLINE (via PubMed) from inception to March 2022
  • Two authors independently assessed studies and extracted data

Pooled result

As reported in the abstract

SLE patients objectively meeting World Health Organization (WHO) physical activity (PA) recommendations (low vs general population)

11% to 29.8%

Impaired aerobic capacity, VO2max (ml/kg/min)

18.8 to 25.78

Safety

No severe adverse event reported across included studies

Original publication

Benefits & risks of physical activity in patients with Systemic Lupus Erythematosus: a systematic review of the literature. Semin Arthritis Rheum. Published 19 November 2022. doi:10.1016/j.semarthrit.2022.152128

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