Lupus & antiphospholipid syndrome

Alexithymia in systemic lupus erythematosus: A cross sectional study in a Brazilian sample

LupusPublished Cross-sectional study

Authors' conclusion

We found a high prevalence of alexithymia in this sample of SLE patients that negatively associated with quality of life, but not with cumulative damage index.

Study context

Population
SLE patients, Brazilian sample90.3% females
Participants
93 patients
Outcome
Prevalence of alexithymia (TAS-26)

Main finding

As reported in the abstract

Alexithymia

55.9%

No alexithymia

22 of 92

23.9%

Inconclusive results

19 of 93

20.4%

Observational data: associations, not effects.

Further findings

Factors associated with alexithymia

Positive association with age
P = 0.01
Negative association with glomerulonephritis (25% vs 59%)
P = 0.005
Negative association with GC use (19.2% vs 59.0%)
P = 0.0007

Correlation of TAS-26 with quality of life (SF-12) and cumulative damage

Correlation with SF-12 mental domain (r = −0.46)
P < 0.0001
Correlation with SF-12 physical domain (r = −0.32)
P = 0.004
No correlation with cumulative damage index (SLICC/ACR DI)

Original publication

Alexithymia in systemic lupus erythematosus: A cross sectional study in a Brazilian sample. Lupus. Published 18 November 2022. doi:10.1177/09612033221139788

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