Lupus & antiphospholipid syndrome
Bacterial infection in patients with juvenile systemic lupus erythematosus and fever
Authors' conclusion
Bacterial infection was detected in 17% of JSLE patients with fever. Procalcitonin > 0.9 ng/mL is a critical marker for identifying bacterial infection.
Study context
- Population
- Patients with juvenile SLE presenting with fever
- Participants
- 116 patients
- Outcome
- Factors associated with bacterial infection
Main finding
As reported in the abstract
Bacterial infection
- Bacterial infection identified
- 17%
- Procalcitonin (PCT) > 0.9 ng/mL retained significance in adjusted model
- p < 0.01
- Nagelkerke's R2
- 0.65
Observational data: associations, not effects.
Original publication
Bacterial infection in patients with juvenile systemic lupus erythematosus and fever. Pediatr Rheumatol Online J. Published 8 April 2025. doi:10. 1186/ s12969-025-01088-1
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