Rheumatoid arthritis

Avoidable Hospitalizations in Persons With Rheumatoid Arthritis: A Population‐Based Study Using Administrative Data

Arthritis Care Res (Hoboken)Published Population-based matched cohort study

Main finding · Hospitalization for heart failure and pulmonary edemaResult — go to the resultIncidence rate ratio 1.12 95% CI 1.01–1.25

Authors' conclusion

Persons with RA are at a higher risk of potentially avoidable hospitalizations three and five years after diagnosis compared to those without RA.

Study context

Population
Persons with rheumatoid arthritis (RA) and age- and sex-matched general population controls, administrative data, 2002 to 2023matched cohort
Participants
83,811 vs 190,304
Exposure
RA vs matched general population controls without RA
  • RAn = 83,811
  • Without RAn = 190,304reference
Outcome
Incidence rates of avoidable hospitalizations (hospitalizations for ambulatory care sensitive conditions)
Follow-up
Three and five years from the date of diagnosis
Methodological detailsadministrative data, 4 general population controls matched to each RA case by age and sex, multivariable regression adjusted for age, sex and location of residence, Cox proportional hazards model
  • Administrative data
  • 4 general population controls matched to each RA case by age and sex
  • Multivariable regression adjusted for age, sex and location of residence
  • Cox proportional hazards model

Main finding

As reported in the abstract

Hospitalization for heart failure and pulmonary edema

Incidence rate ratio

1.12

95% CI 1.01–1.25

RAvs Without RA
IRR 1.12 (95% CI 1.01–1.25)

Observational data: associations, not effects.

Further findings

Predictors of ACSC hospitalizations among RA cases

Comorbid condition that was an ACSC, HR
10.1 (95% CI 7.8-13.0)
Increasing age, prolonged exposure to GC and having comorbid conditions were significant predictors
  • Cox proportional hazards model

Original publication

Avoidable Hospitalizations in Persons With Rheumatoid Arthritis: A Population‐Based Study Using Administrative Data. Arthritis Care Res (Hoboken). Published 2 May 2025. doi:10.1002/acr.25541

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