Systemic sclerosis & Raynaud's

Automated Hand Flexor Tendon–Thickness Measurement in Systemic Sclerosis

Arthritis Care Res (Hoboken)Published Diagnostic accuracy study

Authors' conclusion

Automated analysis of longitudinal hand ultrasonography images enables accurate measurement of flexor tendon thickness.

Study context

Population
Patients with systemic sclerosis (SSc); longitudinal hand US images from the multicenter HANDSOME cohorttraining 59, testing 15 individuals
Comparison
Automated deep learning-based flexor tendon-thickness measurement vs manual expert measurement
Outcome
Agreement and accuracy of automated tendon-thickness measurement (testing dataset)
Methodological detailsproof-of-concept, multicentre cohort, deep learning (nnU-Net), independent testing dataset
  • Proof-of-concept
  • Multicentre cohort
  • Deep learning (nnU-Net)
  • Independent testing dataset

Performance

As reported in the abstract

Automated measurements successfully obtained
100%
Dice similarity coefficient, flexor tendon
0.90
Dice similarity coefficient, proximal phalanx base
0.83
Dice similarity coefficient, metacarpal head
0.76
ICC, automated vs manual thickness
0.83
Mean absolute measurement error
0.25 mm
Relative measurement error
8.0%
Automated segmentations clinically acceptable (visual expert evaluation)
90%

Original publication

Automated Hand Flexor Tendon–Thickness Measurement in Systemic Sclerosis. Arthritis Care Res (Hoboken). Published 25 August 2026. doi:10.1002/acr.80149

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