Associations between power Doppler ultrasound findings and B-mode synovitis and clinical arthritis in juvenile idiopathic arthritis using a standardised scanning approach and scoring system
Authors' conclusion
Increasing severity of PD findings were significantly associated with BM synovitis and with clinical arthritis.
Study context
- Population
- Juvenile idiopathic arthritis (JIA) patients with suspected clinical arthritis21 girls · 6 boys
- Participants
- 27 patients
- Outcome
- PD findings (grades 0-3) in joint regions with BM synovitis, and their associations with BM synovitis, clinical arthritis, patient characteristics and disease activity
Methodological detailssingle experienced ultrasonographer blinded to clinical findings, standardised scanning protocol and joint-specific scoring system with reference atlas, multilevel mixed-effects ordered regression
- Single experienced ultrasonographer blinded to clinical findings
- Standardised scanning protocol and joint-specific scoring system with reference atlas
- Multilevel mixed-effects ordered regression
Main finding
As reported in the abstract
PD findings in joint regions with BM synovitis
- Joint regions evaluated by US
- 971
- Joint regions with B-mode (BM) synovitis (assessed for power Doppler (PD))
- 129
- Joint regions with PD findings
- 45 (34.9%)
- PD findings, most frequent site: parapatellar recess of the knee
- 24.4%
- Increasing PD grades associated with higher BM grades, OR
- 5.0 (p<0.001)
- Increasing PD grades associated with clinical arthritis, OR
- 7.4 (p<0.001)
Observational data: associations, not effects.
Original publication
Associations between power Doppler ultrasound findings and B-mode synovitis and clinical arthritis in juvenile idiopathic arthritis using a standardised scanning approach and scoring system. RMD Open. Published 24 March 2023. doi:10.
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