Association of Rheumatoid Arthritis With Postfracture Mortality and Fracture-Related Care
Main finding · Death after fractureResult — go to the resultHazard ratio 1.28 95% CI 1.18–1.39Authors' conclusion
Using data from hospitals in Western Australia, this study demonstrates that people with RA have worse survival after fracture, and, in contrast to expectation, this survival has not improved despite significant therapeutic advances over the past 40 years.
Study context
- Population
- Patients with rheumatoid arthritis (RA) and matched controls after a first fracture, public and private hospitals in Western Australia, 1990–20101,304 RA patients
- Exposure
- RA vs matched controls
- RAn = 1,304
- Outcome
- Survival after a first fracture (death)
Methodological detailscase-control matched, administrative health data from public and private hospitals
- Case-control matched
- Administrative health data from public and private hospitals
Main finding
Death after fracture
Hazard ratio
1.28
95% CI 1.18–1.39
RAvs Controls
HR 1.28 (95% CI 1.18–1.39)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | |
|---|---|---|
| Episodes of hospital-based care | 1.27 (1.08–1.48) | |
| 0.512Odds ratio (log scale) |
| Outcome | RA | Controls |
|---|---|---|
| Change in postfracture survival, 1990-1999 vs 2000-2010 (within each group) | ||
| HR | 0.95 | 0.86 |
| 95% CI | 0.75-1.20 | 0.71-1.04 |
Change in postfracture survival, 1990-1999 vs 2000-2010 (within each group)
- Postfracture survival did not improve from 1990-1999 to 2000-2010 in RA or controls
Original publication
Association of Rheumatoid Arthritis With Postfracture Mortality and Fracture-Related Care. J Rheumatol. Published 15 November 2025. doi:10.
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