Association of Physical Therapy Care With Use of Intra‐Articular Injections in People With Knee Osteoarthritis: A Real‐World Cohort Study
Main finding · Future intra-articular therapy, PT initiation at 9 to 12 months vs within a month (prior intra-articular therapies)Result — go to the resultAdjusted relative risk 1.44 95% CI 1.35–1.55Authors' conclusion
Initiating PT earlier and more than 12 PT sessions were significantly associated with lower risk of future intra-articular therapy use in people with newly diagnosed knee OA.
Study context
- Population
- American adults with incident knee osteoarthritis (OA) referred for physical therapy (PT) within the first year of diagnosis (age 61.5 ± 11 years, 61% female)
- Participants
- 67,245 adults
- Exposure
- PT timing, number of sessions and type (active vs passive) and future intra-articular therapy use
- Prior intra-articular therapiesn = 34,804
- No prior intra-articular therapiesn = 32,441
- Outcome
- Future intra-articular therapy use
- Follow-up
- One year following the first year of diagnosis
Methodological detailsclaims database (Optum Labs Data Warehouse), real-world
- Claims database (Optum Labs Data Warehouse)
- Real-world
Main finding
As reported in the abstract
Future intra-articular therapy, PT initiation at 9 to 12 months vs within a month (prior intra-articular therapies)
Adjusted relative risk
1.44
95% CI 1.35–1.55
PT initiated at 9 to 12 months post diagnosisvs PT initiated within a month
adjusted RR 1.44 (95% CI 1.35–1.55)
- ≥13 PT sessions vs 1 to 5 sessions, prior intra-articular therapies: lower risk
- 10%
- ≥13 PT sessions vs 1 to 5 sessions, no prior intra-articular therapies: lower risk
- 12%
Observational data: associations, not effects.
Original publication
Association of Physical Therapy Care With Use of Intra‐Articular Injections in People With Knee Osteoarthritis: A Real‐World Cohort Study. Arthritis Rheumatol. Published 2 April 2025. doi:10.
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