Autoinflammatory & rare systemic diseases
Association of Mediterranean diet adherence with familial Mediterranean fever severity in a Lebanese cohort
Authors' conclusion
Our findings reinforce the multifactorial aspect of FMF
Study context
- Population
- Confirmed individuals with Familial Mediterranean Fever (FMF) in Lebanon
- Participants
- 101 individuals
- Exposure
- Low vs moderate vs high Mediterranean diet adherence
- Outcome
- Association between MD adherence and FMF severity (International Severity Score for FMF, International Severity Score for FMF (ISSF))
Methodological detailssurvey, questionnaire-based
- Survey
- Questionnaire-based
Main finding
As reported in the abstract
FMF severity (ISSF) by MD adherence
Observational data: associations, not effects.
Further findings
MD component intakes
- Most MD component intakes did not meet the recommended ranges
Diarrhoea by MD adherence
- Differed significantly, higher frequency in the low MD group
Factors associated with FMF severity
- Obesity, high physical activity and comorbidities (particularly rheumatoid manifestations, IBD, CVD) associated with significantly increased FMF severity
- None emerged as independent predictors in multivariate models
Original publication
Association of Mediterranean diet adherence with familial Mediterranean fever severity in a Lebanese cohort. Pediatr Rheumatol Online J. Published 21 November 2025. doi:10.
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