Spondyloarthritis & psoriatic arthritis
Association between SARC-F as a self-report screening tool for sarcopenia and muscle strength, physical performance, daily activity, patient-reported outcomes and body composition in patients with spondyloarthritis
Authors' conclusion
SARC-F was significantly associated with disease activity, muscle strength and physical performance, but showed limited ability to identify DXA-defined sarcopenia.
Study context
- Population
- Patients with SpA (axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA))65.7% axSpA, 34.3% PsA
- Participants
- 213 patients
- Exposure
- SARC-F score ≥4 vs <4
- SARC-F ≥4n = 54
- Outcome
- Association of SARC-F with muscle strength, physical performance, daily activity, PROs and body composition (DXA)
Methodological detailslinear regression adjusted for age and sex
- Linear regression adjusted for age and sex
Main finding
As reported in the abstract
SARC-F score ≥4 (prevalence)
SARC-F score ≥4
54 of 213
24.4%
Observational data: associations, not effects.
Further findings
- Accuracy of SARC-F ≥4 for DXA-defined sarcopenia
- 76% · specificity · sensitivity 50% · NPV 97%
DXA-defined sarcopenia and sarcopenic obesity
Patients
- Sarcopenia (DXA)
- 4 (7.7%)
- Sarcopenic obesity (DXA)
- 4 (7.7%)
Original publication
Association between SARC-F as a self-report screening tool for sarcopenia and muscle strength, physical performance, daily activity, patient-reported outcomes and body composition in patients with spondyloarthritis. RMD Open. Published 13 March 2026. doi:10.
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