Spondyloarthritis & psoriatic arthritis
Arrhythmic risk stratification in psoriatic arthritis: a retrospective, electrogram-based comparative analysis
Authors' conclusion
Patients with PsA are at a significantly increased risk for ECG abnormalities related to both atrial and ventricular repolarisation as well as atrioventricular conduction.
Study context
- Population
- Patients with psoriatic arthritis (PsA) presenting to one centre 2014–2022 and age- and sex-matched cardiovascular patients (mean age 52.5±13.4 years)matched cohort
- Participants
- 725 vs 725
- Exposure
- PsA vs matched cardiovascular patients
- PsAn = 725
- Controlsn = 725reference
Methodological detailsage-matched and sex-matched controls, single-centre, electrogram-based comparative analysis, Median PsA duration 2 years
- Age-matched and sex-matched controls
- Single-centre
- Electrogram-based comparative analysis
- Median PsA duration 2 years
Further findings
First-degree AV block (AVB I°)
P = 0.725
Significant P-wave terminal force in V1 (excluding known atrial arrhythmias)
P < 0.001
| Outcome | PsA | Controls | P value |
|---|---|---|---|
| Corrected Tpeak-Tend interval | 0.26 ± 0.04 | 0.23 ± 0.05 | P < 0.001 |
| AVB I° within PsA by sex (age-adjusted)Male vs Female · after adjusting for age | P = 0.006 | ||
| AVB I° within PsA by disease duration (age-adjusted)Long disease duration vs Shorter disease duration · after adjusting for age | P < 0.001 |
- AVB I° within PsA by sex (age-adjusted): Male 16.4%
- AVB I° within PsA by sex (age-adjusted): Female 7.1%
- AVB I° within PsA by disease duration (age-adjusted): Long disease duration 18.0%
- AVB I° within PsA by disease duration (age-adjusted): Shorter disease duration 6.9%
Original publication
Arrhythmic risk stratification in psoriatic arthritis: a retrospective, electrogram-based comparative analysis. RMD Open. Published 24 June 2026. doi:10.
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