Application of vascular index based on superb microvascular imaging technique for assessing disease activity in rheumatoid arthritis patients with signal-positive joints
Authors' conclusion
As a quantitative indicator to assess synovitis activity of RA patients, SMI-based VI was helpful in assessing RA disease activity.
Study context
- Population
- Rheumatoid arthritis (RA) patients who underwent superb microvascular imaging (SMI) of 28 joints
- Participants
- 119 patients
- Comparison
- SMI-based vascular index (VI) parameters vs Disease Activity Score (DAS28) disease activity
- Outcome
- Correlation of VI parameters with DAS28 and clinical/laboratory indicators; ability to identify DAS28 <2.6/DAS28 ≤3.2 (ROC)
Performance
As reported in the abstract
Correlation with DAS28
| Test or model | R with DAS28 |
|---|---|
| VIsum | 0.740 |
| VIstand | 0.659 |
R with DAS28
VIsum0.740
VIstand0.659
- Correlation of VIsum and VIstand with DAS28
- P < 0.05
- Differences of VIsum and VIstand among the 4 disease activity groups statistically significant
- P < 0.05
Further findings
| Outcome | VIsum |
|---|---|
| Identification of DAS28 <2.6/DAS28 ≤3.2 (ROC) | |
| Cut-off for DAS28 <2.6/DAS28 ≤3.2 | 35.5/47.8 |
| AUC for DAS28 <2.6/DAS28 ≤3.2 | 0.872/0.846 |
Identification of DAS28 <2.6/DAS28 ≤3.2 (ROC)
- VIsum had higher diagnostic efficacy than VIstand for identifying remission or low and below activity
Original publication
Application of vascular index based on superb microvascular imaging technique for assessing disease activity in rheumatoid arthritis patients with signal-positive joints. Clin Exp Rheumatol. Published 25 November 2024. doi:10.
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