Management of Rheumatoid Arthritis With a Digital Health Application: A Multicenter, Pragmatic Randomized Clinical Trial
An erratum to this article was published (JAMA Netw Open, 1 May 2023 ↗)
Primary result · DAS28-CRP ≤3.2Result — go to the resultDifference 6.6% 95% CI 2.7%–10.4%Authors' conclusion
In this randomized clinical trial of RA, the use of a digital health application with patient-reported outcomes was associated with an increase in disease control rate.
Study context
- Population
- Adult patients with rheumatoid arthritis (RA), 22 tertiary hospitals across China2,204 randomized
- Participants
- 2,197 patients
- Comparison
- Smart system of disease management (SSDM) digital health application vs conventional care
- SSDMn = 1,099
- Controln = 1,098reference
- Primary endpoint
- Rate of patients with DAS28-CRP of 3.2 or less
- Follow-up
- Month 6
Methodological detailsmulticentre, open-label, 1:1 randomisation (block size of 4), blinded outcome assessors and statisticians, 6-month extension with SSDM for control, Enrolment November 1, 2018, to May 28, 2019; 12-month follow-up
- Multicentre
- Open-label
- 1:1 randomisation (block size of 4)
- Blinded outcome assessors and statisticians
- 6-month extension with SSDM for control
- Enrolment November 1, 2018, to May 28, 2019; 12-month follow-up
Primary result
DAS28-CRP ≤3.2
Difference
6.6%
95% CI 2.7%–10.4%
P = 0.001
Events by treatment group
SSDMvs Control
difference 6.6% (95% CI 2.7%–10.4%); P = 0.001
As reported in the abstract
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Management of Rheumatoid Arthritis With a Digital Health Application: A Multicenter, Pragmatic Randomized Clinical Trial. JAMA Netw Open. Published 3 April 2023. doi:10.
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