Lupus & antiphospholipid syndrome
Anxiety in childhood onset lupus: Longitudinal anxiety symptom screening
Authors' conclusion
Anxiety symptoms were common in this cohort of cSLE, and anxiety and depression were significantly associated.
Study context
- Population
- Patients ≥12 years of age diagnosed with cSLE
- Participants
- 76 patients196 visits
- Outcome
- Prevalence of anxiety symptoms (GAD-7; significant if score ≥10)
Methodological detailslongitudinal, electronic health record data
- Longitudinal
- Electronic health record data
Main finding
As reported in the abstract
At least one GAD-7 of mild, and moderate or severe anxiety
At least one GAD-7 of mild anxiety
47%
At least one GAD-7 of moderate or severe anxiety
21%
Observational data: associations, not effects.
Further findings
Association of baseline clinical features with GAD-7 scores
- History of LN and GC dose not associated with GAD-7 scores
Deprivation and Community Index by anxiety status
- Did not vary by anxiety status
Multivariate longitudinal analysis
- Depression associated with clinically significant Generalized Anxiety Disorder (GAD) scores
- No association between anxiety and disease activity, steroid use, pain, physical function, or social factors
Original publication
Anxiety in childhood onset lupus: Longitudinal anxiety symptom screening. Lupus. Published 10 February 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →