Anti-Jo-1 autoantibodies: biomarkers of severity and evolution of the disease in antisynthetase syndrome
Authors' conclusion
Our results suggest that anti-Jo-1 autoantibody concentration could be a predictive marker of the severity and evolution of ASS
Study context
- Population
- Antisynthetase syndrome (ASS) patients with at least one positive anti-Jo-1 measure, 2015–202029 with ≥2 determinations
- Participants
- 48 patients
- Exposure
- Anti-Jo-1 concentrations vs ASS severity and activity
- Outcome
- Anti-Jo-1 concentration vs severity and activity
Main finding
As reported in the abstract
P = 0.016
- Correlation of anti-Jo-1 with MITAX (r), p = 0.03
- 0.4
- Correlation of anti-Jo-1 with creatine kinase (r), p = 0.002
- 0.34
- Correlation of anti-Jo-1 fluctuations with MITAX during follow-up (r), p < 0.0001
- 0.7
Observational data: associations, not effects.
Original publication
Anti-Jo-1 autoantibodies: biomarkers of severity and evolution of the disease in antisynthetase syndrome. Arthritis Res Ther. Published 22 July 2023. doi:10.
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