Vasculitis & polymyalgia rheumatica

An analysis of the first relapse in giant cell arteritis using ultrasonography

Semin Arthritis RheumPublished Observational study

Authors' conclusion

Relapsing disease is more common in the extracranial arteries and may be mistaken for polymyalgia rheumatica. True polymyalgia rheumatica relapses are uncommon.

Study context

Population
Patients with suspected new and relapsing GCA, January 2017 to December 2023
Participants
66 patients
Exposure
First relapse vs baseline disease on ultrasonography
Outcome
Nature of first relapse of GCA compared to baseline disease on ultrasonography (superficial temporal, axillary or mixed disease)
Methodological detailsprotocolised ultrasonography
  • Protocolised ultrasonography

Main finding

As reported in the abstract

Arterial involvement on ultrasonography

Superficial temporal artery involvement, diagnosis

48 of 66

Superficial temporal artery involvement, first relapse

20 of 66

Axillary artery involvement, diagnosis

23 of 66

Axillary artery involvement, first relapse

40 of 66

Observational data: associations, not effects.

Further findings

Patients with PMR relapse
7/66
Of those, superficial temporal arterial involvement at diagnosis
5 of those 7

Original publication

An analysis of the first relapse in giant cell arteritis using ultrasonography. Semin Arthritis Rheum. Published 29 January 2025. doi:10.1016/j.semarthrit.2025.152646

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