An analysis of clinical manifestations and therapeutic outcomes in pediatric connective tissue disease-associated interstitial lung disease
Authors' conclusion
Pediatric CTD-ILD often has an insidious onset with non-specific respiratory symptoms.
Study context
- Population
- Pediatric CTD-ILD patients with complete follow-up data, June 2018 to February 2024
- Participants
- 50 patients
- Outcome
- Pulmonary function and HRCT outcomes after corticosteroid and immunosuppressant treatment
- Follow-up
- 6 and 12 months; HRCT at 1 year
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
- Pulmonary function improved significantly at 6 and 12 months
- P < 0.05
Observational data: associations, not effects.
Further findings
Pulmonary function · 6 and 12 months
- Improved significantly
- P < 0.05
HRCT · 1 year
- Radiological improvement in all patients, no progression
Original publication
An analysis of clinical manifestations and therapeutic outcomes in pediatric connective tissue disease-associated interstitial lung disease. Pediatr Rheumatol Online J. Published 21 March 2026. doi:10. 1186/ s12969-026-01208-5
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