Pediatric rheumatology

An analysis of clinical manifestations and therapeutic outcomes in pediatric connective tissue disease-associated interstitial lung disease

Pediatr Rheumatol Online JPublished Retrospective cohort study

Authors' conclusion

Pediatric CTD-ILD often has an insidious onset with non-specific respiratory symptoms.

Study context

Population
Pediatric CTD-ILD patients with complete follow-up data, June 2018 to February 2024
Participants
50 patients
Outcome
Pulmonary function and HRCT outcomes after corticosteroid and immunosuppressant treatment
Follow-up
6 and 12 months; HRCT at 1 year
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Pulmonary function improved significantly at 6 and 12 months
P < 0.05

Observational data: associations, not effects.

Further findings

Pulmonary function · 6 and 12 months

Improved significantly
P < 0.05

HRCT · 1 year

Radiological improvement in all patients, no progression

Original publication

An analysis of clinical manifestations and therapeutic outcomes in pediatric connective tissue disease-associated interstitial lung disease. Pediatr Rheumatol Online J. Published 21 March 2026. doi:10.1186/s12969-026-01208-5

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