Adherence to medication during pregnancy in systemic autoimmune diseases: results from a prospective study
Authors' conclusion
In our cohort we recorded a good adherence to prescribed medication, although adequate adherence was not achieved in about 30% of patients, confirming that non-adherence is an important issue in SAD.
Study context
- Population
- Patients with systemic autoimmune diseases (SAD)
- Participants
- 200 patients
- Exposure
- Pregnant vs non-pregnant women with SAD
- Pregnantn = 100
- Non-pregnantn = 100reference
- Outcome
- Medication adherence (MMAS-8), for HCQ and for other treatments for rheumatic disease
Methodological detailsconsecutive enrolment
- Consecutive enrolment
Main finding
As reported in the abstract
Good medication adherence (MMAS-8)
Good medication adherence (MMAS-8)
Good adherence, other therapies
Observational data: associations, not effects.
Further findings
Very poor medication adherence
- Eight patients had very poor adherence, all non-pregnant women
- 8
Anxiety and low medication adherence (drugs other than hydroxychloroquine (HCQ))
- Anxiety (15% of patients) associated with low adherence for drugs other than HCQ
- P = 0.02
- Depression (4% of patients) did not seem to impact adherence
Original publication
Adherence to medication during pregnancy in systemic autoimmune diseases: results from a prospective study. Clin Exp Rheumatol. Published 7 July 2023. doi:10.
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