Acute coronary syndrome in calcium pyrophosphate deposition disease patients: A US inpatient care cohort study
Main finding · In-hospital mortalityResult — go to the resultOdds ratio 0.77 95 % CI 0.70–0.85Authors' conclusion
ACS in CPPD patients is associated with higher healthcare utilization, including cost and length of hospital stay, and lower in-hospital mortality than non-CPPD patients.
Study context
- Population
- Patients admitted for acute coronary syndrome (ACS), US National Inpatient Sample (NIS) Database, 2006–2019admitted for ACS
- Participants
- 17,322,362 patients
- Exposure
- ACS admissions with CPPD vs without CPPD
- CPPDn = 7,458
- Outcome
- In-hospital mortality, LOS, hospital charges and in-hospital complications
Methodological detailsUS National Inpatient Sample (NIS) Database, ICD-9 and −10 codes
- US National Inpatient Sample (NIS) Database
- ICD-9 and −10 codes
Main finding
In-hospital mortality
Odds ratio
0.77
95 % CI 0.70–0.85
CPPDvs Non-CPPD
OR 0.77 (95 % CI 0.70–0.85)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | OR (95 % CI) | |
|---|---|---|
| Mean LOS | 3.35 (3.17–3.53) | |
| Mean total charges | 1.04 (1.01–1.10) | |
| 0.20.5125Odds ratio (log scale) |
Age
P < 0.001
CKD
- More frequent in CPPD patients
Safety
Acute ischaemic stroke and post-procedural haemorrhage (in-hospital complications)
- More frequently seen in CPPD patients
Original publication
Acute coronary syndrome in calcium pyrophosphate deposition disease patients: A US inpatient care cohort study. Semin Arthritis Rheum. Published 17 May 2024. doi:10.
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