A patient-centred assessment of the 2016 ACR-EULAR Myositis Response Criteria: evaluating the meaningfulness of responses
Authors' conclusion
Achieving improvement criteria was accompanied by significant clinical improvements in fatigue, pain, health-related quality of life, physical function, and physical activity.
Study context
- Population
- Adults with myositis (PM, DM, necrotizing myopathy, ASyS)mean age 52, 60% female
- Participants
- 50 adults
- Exposure
- Minimal Total Improvement Score (TIS) improvement vs no improvement
- Outcome
- Association between achieving TIS improvement and patient-centred outcome measures (fatigue, pain, health-related quality of life, physical function, physical activity)
- Follow-up
- 6 months
Methodological detailsbaseline and 6-month visits
- Baseline and 6-month visits
Main finding
As reported in the abstract
PCOMs by TIS improvement category
- 21 patients satisfied the TIS improvement criteria at 6 months
- Patient-centred outcome measures (PCOMs) including fatigue, pain, quality of life, physical activity and physical function demonstrated significantly greater improvement with minimal TIS improvement vs no improvement
- Greater PCOM improvements were seen with moderate-major TIS improvement
- TIS had moderate-strong correlations with most PCOMs
Observational data: associations, not effects.
Original publication
A patient-centred assessment of the 2016 ACR-EULAR Myositis Response Criteria: evaluating the meaningfulness of responses. Rheumatology (Oxford). Published 9 March 2024. doi:10.
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