A multidisciplinary lifestyle program for metabolic syndrome-associated osteoarthritis: the "Plants for Joints" randomized controlled trial
Primary result · WOMAC total score improvementResult — go to the resultMean larger improvement 11 point 95% CI 6–16Authors' conclusion
The "Plants for Joints" lifestyle program reduced stiffness, relieved pain, and improved physical function in people with hip or knee MSOA compared to usual care.
Study context
- Population
- Patients with hip or knee metabolic syndrome-associated OA (MSOA); 84% female, mean (SD) age 63 (6) years, BMI 33 (5) kg/m²64 completed
- Participants
- 66 patients
- Comparison
- 16-week multidisciplinary lifestyle program (whole food plant-based diet, physical activity, stress management) plus usual care vs usual care
- Interventionn = 32
- Primary endpoint
- WOMAC total score (range 0-96)
- Follow-up
- 16 weeks
Primary result
WOMAC total score improvement
Mean larger improvement
11 point
95% CI 6–16
P = 0.0001
As reported in the abstract
Secondary outcomes
| Outcome | Estimate |
|---|---|
| Weight, fat mass and waist circumference · 16 weeksIntervention vs Control | weight −5 kg |
| Weight, fat mass and waist circumference · 16 weeksIntervention vs Control | fat mass −4 kg |
| Weight, fat mass and waist circumference · 16 weeksIntervention vs Control | waist circumference −6 cm |
Other PROs and metabolic measures · 16 weeks
- Patient-Reported Outcomes Measurement Information System (PROMIS) fatigue, pain interference, CRP, hemoglobin A1c, fasting glucose and LDL improved in intervention vs control
- Other PROMIS measures, blood pressure, HDL and triglycerides did not differ significantly between groups
Original publication
A multidisciplinary lifestyle program for metabolic syndrome-associated osteoarthritis: the "Plants for Joints" randomized controlled trial. Osteoarthritis Cartilage. Published 14 June 2023. doi:10.
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